Agenerase

A variety of other drugs may also interact with Agenerase. Here is a list of the major possibilities.

Abacavir (Ziagen)
Amiodarone (Cordarone)
Antacids such as Maalox and Mylanta
Antidepressants classified as "tricyclics," such as Elavil, Pamelor, and Tofranil
Benzodiazepine drugs used to treat anxiety, including Dalmane, Tranxene, Valium, and Xanax
Calcium Channel Blockers (used for high blood pressure and angina), including Adalat, Calan, Cardene, Cardizem, Dilacor, DynaCirc, Nimotop, Norvasc, Plendil, Procardia, Sular, and Vascor
Carbamazepine (Tegretol)
Cholesterol-lowering agents such as Lipitor, Mevacor, and Zocor
Cimetidine (Tagamet)
Clarithromycin (Biaxin)
Clozapine (Clozaril)
Cyclosporine (Sandimmune; Neoral)
Dapsone
Delavirdine (Rescriptor)
Dexamethasone (Decadron)
Didanosine (Videx)
Dihydroergotamine (D.H.E. 45 Injection, Migranal Nasal Spray)
Disulfiram (Antabuse)
Efavirenz (Sustiva)
Ergonovine (Ergotrate)
Ergotamine (Ergostat)
Erythromycin (Eryc, Ery-Tab)
Indinavir (Crixivan)
Itraconazole (Sporanox)
Ketoconazole (Nizoral)
Lidocaine
Lopinavir/ritonavir (Kaletra)
Loratadine (Claritin)
Methadone
Methylergonovine (Methergine)
Metronidazole (Flagyl)
Midazolam (Versed)
Nelfinavir (Viracept)
Nevirapine (Viramune)
Oral contraceptives
Phenobarbital
Phenytoin (Dilantin)
Pimozide (Orap)
Quinidine (Quinaglute, Quinidex)
Rapamycin (Rapamune)
Rifabutin (Mycobutin)
Rifampin (Rifadin, Rimactane)
Ritonavir (Norvir)
St. John's wort
Saquinavir (Invirase)
Sildenafil (Viagra)
Tacrolimus (Prograf)
Triazolam (Halcion)
Warfarin (Coumadin)
Zidovudine (Retrovir)

Special information if you are pregnant or breastfeeding

The effects of Agenerase during pregnancy have not been adequately studied. If you are pregnant or plan to become pregnant, tell your doctor immediately. Do not take the oral solution while pregnant.

Since HIV infection can be passed to your baby through breast milk, you should avoid breastfeeding.

Recommended dosage

ADULTS

Capsules

The usual dosage for adults and adolescents 13 years of age and over is 1,200 milligrams (eight 150-milligram capsules) twice a day in combination with other anti-HIV medications. When combined with Norvir, the recommended dosage is 1,200 milligrams of Agenerase and 200 milligrams of Norvir once a day, or half that amount twice a day.