Avelox

You should avoid Avelox if you have a low level of potassium in your blood. Low potassium can be caused by the water pills (diuretics) often prescribed for high blood pressure. If you are taking a diuretic, make sure the doctor knows about it before you begin treatment with Avelox.

A case of diarrhea during Avelox therapy could signal development of a potentially dangerous bowel inflammation. Call your doctor for treatment at the first sign of a problem.

Avelox has not been tested in children under 18.

Possible food and drug interactions when taking Avelox

Multivitamins containing iron or zinc; antacids containing magnesium, calcium, or aluminum; sucralfate; or didanosine reduce the effectiveness of Avelox. Take it at least 4 hours before or 8 hours after any of these products.

Do not take Avelox with nonsteroidal anti-inflammatory drugs (NSAIDs) such as Advil, Motrin, and Naprosyn because it may increase the risk of nerve stimulation and convulsions.

Other drugs to use cautiously while taking Avelox include:

• Amiodarone
• Antipsychotic drugs such as chlorpromazine, haloperidol, and trifluoperazine
• Erythromycin
• Procainamide
• Quinidine
• Sotalol
• Tricyclic antidepressants such as amitriptyline hydrochloride, desipramine hydrochloride, and perphenazine
• Warfarin

You also should avoid Avelox if the amount of potassium in your blood is low. Low potassium can sometimes be caused by diuretic medications such as Lasix. If you are taking a diuretic medicine, tell your doctor before taking Avelox. In fact, inform your doctor of all medications you are taking, including over-the-counter remedies.

Special information if you are pregnant or breastfeeding

The effects of Avelox during pregnancy have not been studied. It should be used during pregnancy only if the benefits outweigh the possible risk to the unborn baby. If you are expecting, make sure the doctor is aware of it before you start taking this drug.

Avelox may appear in breast milk and could affect a nursing infant. If this medication is essential to your health, your doctor may advise you to discontinue breastfeeding until your treatment is finished.