Calan

If you are taking Covera-HS and you have a narrowing in your stomach or intestines, be sure your doctor was aware of it when the drug was prescribed.

The outer shell of Covera-HS does not dissolve; do not worry if you see it in your stool.

Possible food and drug interactions when taking Calan

If verapamil is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining verapamil with the following:

• ACE inhibitor-type blood pressure drugs such as captopril and enalapril maleate
• Beta-blocker-type blood pressure drugs such as atenolol, metoprolol tartrate, and propranolol hydrochloride
• Vasodilator-type blood pressure drugs such as minoxidil
• Other high blood pressure drugs such as prazosin hydrochloride
• Alcohol
• Aspirin
• Amiodarone
• Carbamazepine
• Chloroquine
• Cimetidine
• Cyclosporine
• Dantrolene
• Digitalis
• Disopyramide
• Diuretics such as furosemide and hydrochlorothiazide
• Erythromycin
• Flecainide
• Glipizide
• Grapefruit juice
• Imipramine
• Lithium
• Nitrates such as isosorbide dinitrate and nitroglycerin
• Phenobarbital
• Phenytoin
• Quinidine
• Rifampin
• Ritonavir
• Theophylline

Special information if you are pregnant or breastfeeding

The effects of verapamil during pregnancy have not been adequately studied. If you are pregnant or plan to become pregnant, inform your doctor immediately. The drug appears in breast milk and could affect a nursing infant. If this medication is essential to your health, your doctor may advise you to discontinue breastfeeding until your treatment is finished.

Recommended dosage for Calan

FOR CALAN AND ISOPTIN

Dosages of this medication must be adjusted to meet individual needs. In general, dosages of this medication should not exceed 480 milligrams per day. Your doctor will closely monitor your response to this drug, usually within 8 hours of the first dose.

Safety and effectiveness of this drug in children have not been established.