Colazal

Pronounced: KOHL-a-zahl
Generic name: Balsalazide disodium

Why is Colazal prescribed?

Colazal is used in the treatment of mild to moderate ulcerative colitis (chronic inflammation and ulceration of the lower intestine). It is an anti-inflammatory medicine specially formulated to release the active ingredient, mesalamine, directly to the lining of the colon. Its ability to provide relief without the severe side effects found with similar drugs is believed to be due to this localized drug delivery mechanism.

Most important fact about Colazal

Although there have been no reports of kidney damage from Colazal, other products containing mesalamine are known to have caused this problem. If you have kidney disease, your doctor will monitor your condition closely during treatment with Colazal. Report any problems or unusual symptoms immediately.

How should you take Colazal?

Colazal can be taken with or without food.

--If you miss a dose...

Take it as soon as possible. If it is within two hours of your next dose, skip the one you missed and go back to your regular schedule. Do not take two doses at once.

--Storage instructions...

Store at room temperature.

What side effects may occur?

Side effects cannot be anticipated. If any develop or change in intensity, inform your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking Colazal.

• More common side effects may include:
  Abdominal pain, diarrhea, headache, joint pain, nausea, vomiting, respiratory infection

Why should Colazal not be prescribed?

Do not take Colazal if you are allergic to mesalamine (Rowasa) or salicylates such as aspirin.

Special warnings about Colazal

Some cases of fatal liver disease have been reported during treatment with Colazal. If you have a liver problem, make sure your doctor is aware of it before you start treatment.

If you have pyloric stenosis (narrowing of the stomach outlet), Colazal capsules may be slow to pass through the digestive tract.