CombiPatch
Overview
- About CombiPatch
Pronounced: KOM-bee-patch
Generic name: Estradiol and Norethindrone acetate
Why is CombiPatch prescribed?
A remedy for the symptoms of menopause, CombiPatch combines the hormones estrogen (estradiol) and progestin (norethindrone acetate) in a slow-release patch that's applied to the skin. The product eases such symptoms of menopause as feelings of warmth in the face, neck, and chest, and the sudden intense episodes of heat and sweating known as "hot flashes." It is also prescribed to relieve external vaginal irritation and internal vaginal dryness.
CombiPatch can also be used as an estrogen supplement by women unable to produce sufficient amounts of estrogen on their own. Problems prompting the need for supplementation include ovarian failure, hypogonadism (impaired hormone production), and surgical removal of the ovaries.
Most important fact about CombiPatch
Using estrogen may increase your chances of getting heart attacks, strokes, blood clots, breast cancer, and endometrial cancer (cancer in the lining of the uterus). Because estrogen replacement therapy is not advisable if you are in any danger of developing cancer or blood clots, your doctor should take a complete medical and family history, and perform a complete physical exam, before prescribing CombiPatch. It is important to have regular check-ups (at least once a year) and to report any unusual vaginal bleeding to your doctor immediately.
Hormone replacement therapy using estrogens, with or without progestin, should not be used to prevent heart disease. Recent studies have confirmed an increased rate of heart attack, stroke, and dangerous blood clots among women taking estrogen or estrogen combinations for 5 years. Blood clots can lead to phlebitis, stroke, heart attack, a loss of blood supply to the lungs, a blockage in the blood vessels serving the eye, and other serious disorders. Because of these risks hormone replacement therapy should be given at the lowest effective dose for the shortest time. Your doctor will determine the dosage that is best for you.
