Coreg

If you wear contact lenses, you should know that Coreg can dry your eyes.

Possible food and drug interactions when taking Coreg

If Coreg is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Coreg with any of the following:

• Calcium channel blockers (blood pressure and heart medications such as diltiazem and verapamil)
• Cimetidine
• Clonidine
• Cyclosporine
• Diabetes pills such as chlorpropamide and metformin
• Drugs classified as MAO inhibitors, including the antidepressants phenelzine and tranylcypromine
• Digoxin
• Fluoxetine
• Insulin
• Paroxetine
• Propafenone
• Quinidine
• Reserpine
• Rifampin
• You should not drink alcohol (including medicines that contain ethanol) within 2 hours of taking Coreg CR extended-release capsules.

Special information if you are pregnant or breastfeeding

Coreg has not been adequately studied in pregnant women; and it is not known whether the drug appears in breast milk. If you are pregnant or plan to become pregnant, check with your doctor immediately.

Recommended dosage for Coreg

ADULTS

Hypertension

For Coreg: The recommended starting dose is 6.25 milligrams twice a day with food. Your doctor may raise the dosage every 1 or 2 weeks to a maximum of 50 milligrams a day.

For Coreg CR: The recommended starting dose is 20 milligrams once daily in the morning with food. Your doctor may raise the dosage every 1 or 2 weeks to a maximum of 80 milligrams once a day.

Congestive Heart Failure

For Coreg: The starting dose is 3.125 milligrams twice a day with food. Your doctor may increase the dosage every 2 weeks. The maximum dosage, for people weighing over 187 pounds, is 100 milligrams a day.

For Coreg CR: The starting dose is 10 milligrams once daily in the morning with food. Your doctor may increase the dosage every 2 weeks to a maximum of 80 milligrams once a day.

Left Ventricular Dysfunction Following a Heart Attack