Crixivan

People taking HIV medications may also experience a redistribution of body fat, with wasting of the face, arms, and legs, and accumulation of fat around the middle, the upper back, and breasts.

Cases of liver failure and death have occurred in patients treated with Crixivan and other medications. If you have a liver problem, particularly cirrhosis of the liver, make sure the doctor is aware of it. Kidney problems, including kidney and urinary stones, are also a possibility, so alert the doctor if you have any type of kidney disease.

Some patients have developed severe anemia (loss of red blood cells) while taking Crixivan. If this problem surfaces, you will have to stop taking the drug.

If you have hemophilia, you should also be aware that spontaneous bleeding has occurred in hemophilia victims taking protease inhibitors such as Crixivan.

Possible food and drug interactions when taking Crixivan

Avoid the following medications while taking Crixivan. The combination may cause serious or life-threatening effects.

Amiodarone (Pacerone)
Atazanavir (Reyataz)
Cisapride
Ergot-based drugs such as Cafergot, Methergine, Migranal
Lovastatin (Mevacor)
Midazolam (Versed)
Pimozide (Orap)
Rifampin (Rifadin, Rifamate)
Simvastatin (Zocor)
St. John's wort
Triazolam (Halcion)

It's also best to avoid combining Crixivan with St. John's wort, which reduces Crixivan's effect.

Crixivan may interact with certain other drugs, and the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Crixivan with the following:

Bepridil (Vascor)
Carbamazepine (Tegretol)
Cholesterol-lowering drugs such as Lescol, Lipitor, Pravachol
Cimetadine (Tagamet)
Clarithromycin (Biaxin)
Cyclosporine (Neoral, Sandimmune)
Delavirdine (Rescriptor)
Didanosine (Videx)
Efavirenz (Sustiva)
Fluconazole (Diflucan)
Heart medications known as calcium channel blockers, including Cardene, Plendil, and Procardia
Isoniazid (Nydrazid)
Itraconazole (Sporanox)
Ketoconazole (Nizoral)
Lamivudine (Epivir)
Lidocaine (Lidoderm)
Methadone
Nelfinavir (Viracept)
Nevirapine (Viramune)
Ortho-Novum (ethinyl estradiol and norethindrone)
Phenobarbital
Phenytoin (Dilantin)
Quinidine (Quinidex)
Rifabutin (Mycobutin)
Rifampin (Rifadin)
Ritonavir (Norvir)
Saquinavir (Fortovase)
Sirolimus (Rapamune)
Stavudine (Zerit)
Sulfamethoxazole (Bactrim, Septra)
Tacrolimus (Prograf)
Theophylline (Theo-Dur)
Trimethoprim (Bactrim, Trimpex, Septra)
Zidovudine (Retrovir)