DDAVP

If you have cystic fibrosis or any other condition in which there is fluid and electrolyte imbalance, you should use DDAVP with extreme caution.

Because DDAVP may cause a rise in blood pressure, use this medication cautiously if you have high blood pressure and/or coronary artery disease. Your blood pressure could also fall temporarily. If you continue to experience bleeding after using Stimate nasal spray, contact your doctor.

Possible food and drug interactions when taking DDAVP

If DDAVP is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining DDAVP with the following:

• Any drug used to increase blood pressure
• Clofibrate
• Glyburide
• Epinephrine

Special information if you are pregnant or breastfeeding

If you are pregnant or plan to become pregnant, inform your doctor immediately. Although DDAVP is not known to cause birth defects, it should be used with caution. DDAVP should be taken during pregnancy only if clearly needed. DDAVP is not believed to appear in breast milk. However, check with your doctor before using the drug while breastfeeding.

Recommended dosage for DDAVP

Your doctor will carefully tailor your dosage to meet your individual needs.

CENTRAL CRANIAL DIABETES INSIPIDUS

DDAVP Nasal Spray and Nose Drops

Adults: The usual recommended dosage range is 0.1 to 0.4 milliliter daily, either as a single dose or divided into 2 or 3 doses. Most adults require 0.2 milliliter per day divided into 2 doses.

Children: The usual dosage range for children aged 3 months to 12 years is 0.05 to 0.3 milliliter daily, either as a single dose or divided into 2 doses.

DDAVP Tablets

Adults and Children Aged 4 and Over: The usual starting dose is half of a 0.1-milligram tablet twice a day. Your doctor will adjust the dose to suit you. You will eventually take 0.1 to 1.2 milligrams a day, divided into smaller doses.

PRIMARY NOCTURNAL ENURESIS (BEDWETTING)