Demadex
Overview
- About Demadex
Special warnings about Demadex
Return to topIf you have cirrhosis, the doctor will use Demadex with great caution. The fluid and chemical imbalance that the drug can cause could send you into a coma.
Demadex may cause ringing in the ears and potential hearing loss, especially when large doses are given quickly.
In addition to potential imbalances in potassium, sodium, chloride, calcium, magnesium, and nitrogen, Demadex is known to cause a slight increase in blood sugar and cholesterol levels.
Possible food and drug interactions when taking Demadex
Return to topIf Demadex is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Demadex with the following:
- Aminoglycoside antibiotics such as tobramycin and streptomycin
- Aspirin and other nonsteroidal anti-inflammatory drugs such as ibuprofen, indomethacin, and naproxen
- Cholestyramine
- Ethacrynic acid
- Lithium
- Probenecid
Special information if you are pregnant or breastfeeding
Return to topThe effects of Demadex during pregnancy have not been adequately studied. If you are pregnant or plan to become pregnant, inform your doctor immediately.
It is not known whether Demadex appears in breast milk. Use Demadex with caution if you are nursing a baby.
Recommended dosage for Demadex
Return to topADULTS
Congestive Heart Failure
The usual starting dose is 10 or 20 milligrams once a day. If this proves inadequate, the doctor will keep doubling the dose until the drug does its work. Doses of more than 200 milligrams are not recommended.
Chronic Kidney Failure
The usual starting dose is 20 milligrams once a day. If this proves inadequate, the doctor will keep doubling the dose until the drug does its work. Doses of more than 200 milligrams are not recommended.
Cirrhosis of the Liver
The usual starting dose is 5 or 10 milligrams once a day with other medications. If this proves inadequate, the doctor will keep doubling the dose until the drug does its work. Doses of more than 40 milligrams are not recommended.
