Why is this drug prescribed?

Entex LA is used to treat bronchitis, the common cold, sinus inflammation, nasal congestion, and sore throat.

Entex LA is a combination of two medications, phenylpropanolamine (a decongestant) and guaifenesin (an expectorant), specially formulated to deliver prolonged action. Phenylpropanolamine helps reduce congestion in the nasal passages, while guaifenesin breaks up mucus in the lower respiratory tract, making it easier to clear the passages.

Most important fact about this drug

Certain medical conditions can affect your use of Entex LA. If you have heart disease, high blood pressure, or diabetes, make sure the doctor knows about it. The phenylpropanolamine in Entex LA can raise blood pressure and speed up the heart, and can put you at a greater risk of heart or blood-vessel disease if you are diabetic.

How should you take this medication?

You may break Entex LA tablets in half to make them easier to swallow, but you must not chew or crush them.

---If you miss a dose...

Take it as soon as you remember. If it is almost time for your next dose, skip the one you missed and go back to your regular schedule. Never take 2 doses at once.

---Storage instructions...

Store at room temperature in a tightly closed container, away from light.

What side effects may occur?

Side effects cannot be anticipated. If any develop or change in intensity, inform your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking this type of medication.

• Side effects may include:
  Anxiety, convulsions, depression, difficulty breathing, difficulty urinating (in men with an enlarged prostate), hallucinations, headache, inability to sleep or difficulty sleeping, increased heart beat, irritability, irritated stomach, nausea, nervousness, paleness, palpitations, restlessness, tremor, weakness, vomiting

Why should this drug not be prescribed?

You should not use Entex LA if you have severe high blood pressure, are sensitive to other stimulating drugs such as Dristan Decongestant, or take antidepressant medications known as MAO inhibitors, including Nardil and Parnate.

Special warnings about this medication

Use Entex LA cautiously if you have any of the following conditions:

Diabetes
Glaucoma (excessive pressure in the eyes)
Heart disease
High blood pressure
Hyperthyroidism (excessive thyroid gland activity)
Prostate enlargement

Possible food and drug interactions when taking this medication

Do not take Entex LA if you are taking a medication classified as an MAO inhibitor, including the antidepressants Nardil and Parnate. Avoid other stimulating drugs such as Proventil, Ventolin, and many decongestants. Interactions can also occur with the following:

Bromocriptine (Parlodel)
Mecamylamine (Inversine)
Methyldopa (Aldomet)
Reserpine (Diupres, Hydropres)

Special information if you are pregnant or breastfeeding

The effects of Entex LA during pregnancy have not been adequately studied. If you are pregnant or plan to become pregnant, notify your doctor immediately. It is not known whether Entex LA appears in breast milk. If this medication is essential to your health, your doctor may advise you to discontinue breastfeeding until treatment with this drug is finished.

Recommended dosage

ADULTS AND CHILDREN 12 YEARS AND OLDER

The usual dosage is 1 tablet every 12 hours.

CHILDREN 6 TO 12 YEARS OLD

The usual dosage is one-half tablet every 12 hours.

The safety and effectiveness of Entex LA have not been established in children under the age of 6.

Overdosage

Any medication taken in excess can have serious consequences. If you suspect an overdose, seek medical help immediately.

• Symptoms of Entex LA overdose may include:
  Coma, convulsions, high blood pressure