Erythromycin, Oral

Special information if you are pregnant or breastfeeding

There is no evidence that erythromycin will harm a developing baby, but the possibility has not been completely ruled out. If you are pregnant or plan to become pregnant, inform your doctor immediately.

Erythromycin appears in breast milk and could affect a nursing infant. If this medication is essential to your health, your doctor may advise you to discontinue breastfeeding until your treatment is finished.

Recommended dosage

Dosage instructions are determined by the type (and severity) of infection being treated and may vary slightly for different brands of erythromycin. The following are recommended dosages for PCE, one of the most commonly prescribed brands.

ADULTS

Streptococcal Infections

The usual dose is 333 milligrams every 8 hours, or 500 milligrams every 12 hours. Depending on the severity of the infection, the dose may be increased to a total of 4 grams a day. However, when the daily dosage is larger than 1 gram, twice-a-day doses are not recommended, and the drug should be taken more often in smaller doses.

To treat streptococcal infections of the upper respiratory tract (tonsillitis or strep throat), erythromycin should be taken for at least 10 days.

To prevent repeated infections in people who have had rheumatic fever, the usual dosage is 250 milligrams twice a day.

Urinary Tract Infections Due to Chlamydia Trachomatis During Pregnancy

The usual dosage is 500 milligrams of erythromycin orally 4 times a day or 666 milligrams every 8 hours on an empty stomach for at least 7 days. For women who cannot tolerate this regimen, a decreased dose of 500 milligrams every 12 hours or 333 milligrams every 8 hours a day should be used for at least 14 days.

For Those with Uncomplicated Urinary, Reproductive Tract, or Rectal Infections Caused by Chlamydia Trachomatis When Tetracycline Cannot Be Taken

The usual oral dosage is 500 milligrams of erythromycin 4 times a day or 666 milligrams every 8 hours for at least 7 days.

For Those with Nongonococcal Urethral Infections When Tetracycline Cannot Be Taken