Flexeril

Overview

About Flexeril

Special warnings about Flexeril

Flexeril may cause you to become drowsy or less alert; therefore, you should not drive or operate dangerous machinery or participate in any hazardous activity that requires full mental alertness until you know how this drug affects you.

You should use Flexeril with caution if you have ever been unable to urinate or if you have ever had the eye condition called glaucoma.

Possible food and drug interactions when taking Flexeril

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Serious, potentially fatal reactions may occur if you take Flexeril with an antidepressant drug known as an MAO inhibitor (such as phenelzine, tranylcypromine) or if it has been less than 2 weeks since you last took an MAO inhibitor. You should closely follow your doctor's advice regarding discontinuation of MAO inhibitors before taking Flexeril.

Avoid alcoholic beverages while taking Flexeril.

If Flexeril is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Flexeril with the following:

Barbiturates such as phenobarbital
Guanethidine and other high blood pressure drugs
Other drugs that slow the central nervous system, such as alprazolam and triazolam
Tramadol

Special information if you are pregnant or breastfeeding

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The effects of Flexeril during pregnancy have not been adequately studied. If you are pregnant or plan to become pregnant, inform your doctor immediately. It is not known if Flexeril appears in breast milk. However, cyclobenzaprine is related to tricyclic antidepressants, and some of those drugs do appear in breast milk. If this medication is essential to your health, your doctor may advise you to discontinue breastfeeding your baby until your treatment is finished.