Glucotrol

Overview

About Glucotrol

Even people with well-controlled diabetes may find that injury, infection, surgery, or fever results in a lack of control over their diabetes. In these cases, the physician may recommend that you stop taking Glucotrol temporarily and use insulin instead.

Glucotrol may not work well in patients with poor kidney or liver function.

In addition, the effectiveness of any oral antidiabetic, including Glucotrol, may decrease with time. This may occur because of either a diminished responsiveness to the medication or a worsening of the diabetes.

Be careful taking the extended-release form of the drug, Glucotrol XL, if you have any narrowing in your stomach or intestines. Also, if you have any stomach or intestinal disease, Glucotrol XL may not work as well.

Possible food and drug interactions when taking Glucotrol

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It is essential that you closely follow your physician's dietary guidelines and that you inform your physician of any medication, either prescription or nonprescription, that you are taking. Specific medications that affect Glucotrol include:

Airway-opening drugs such as pseudoephedrine
Antacids
Aspirin
Chloramphenicol
Cimetidine
Clofibrate
Corticosteroids such as prednisone
Diuretics such as hydrochlorothiazide
Estrogens
Fluconazole
Gemfibrozil
Heart and blood pressure medications called beta blockers such as atenolol and metoprolol
Heart medications called calcium channel blockers such as diltiazem and nifedipine
Isoniazid
Itraconazole
MAO inhibitors (antidepressant drugs such as Phenelzine and tranylcypromine)
Major tranquilizers such as chlorpromazine and thioridazine
Miconazole
Nicotinic acid
Nonsteroidal anti-inflammatory drugs such as ibuprofen and naproxen
Oral contraceptives
Phenytoin
Probenecid
Rifampin
Sulfa drugs such as sulfamethoxazole
Thyroid medications such as levothyroxine
Warfarin