Imitrex

Possible food and drug interactions when taking Imitrex

If Imitrex is taken with certain other drugs, the effects of either may be increased, decreased, or altered. It is important to check with your doctor before combining Imitrex with the following:

Drugs classified as MAO inhibitors, including the antidepressants Nardil and Parnate
Ergot-containing drugs such as Cafergot and Ergostat
Fluoxetine (Prozac)
Fluvoxamine (Luvox)
Paroxetine (Paxil)
Sertraline (Zoloft)

Special information if you are pregnant or breastfeeding

The effects of Imitrex during pregnancy have not been adequately studied. If you are pregnant or plan to become pregnant, inform your doctor immediately. Imitrex does appear in breast milk and could affect a nursing infant. If this medication is essential to your health, your doctor may advise you to discontinue breastfeeding until your treatment with Imitrex is finished.

Recommended dosage

IMITREX INJECTION

The maximum single recommended adult dose is 6 milligrams injected under the skin.

The maximum recommended dose that may be given within 24 hours is two 6 milligram injections taken at least 1 hour apart.

IMITREX TABLETS

The usual adult dose is one 25-, 50-, or 100-milligram tablet taken with water or other liquid. The most you should take at one time is 100 milligrams, and the most you should take in 1 day is 200 milligrams. Doses should be spaced at least 2 hours apart.

If you have liver disease, you should not take more than 50 milligrams of Imitrex Tablets at one time.

IMITREX NASAL SPRAY

The recommended adult dose ranges from 5 to 20 milligrams taken when the attack begins and repeated once, if necessary, 2 hours later. Doses are usually taken as a single spray in one nostril, but if a 10-milligram dose works best for you, you can take it as a 5-milligram spray in each nostril. Do not use more than 20 milligrams at a time, or take more than 40 milligrams a day.

Overdosage

Any medication taken in excess can have serious consequences. If you suspect an overdose, seek medical attention immediately.

• Symptoms of Imitrex overdose may include:
  Bluish tinge to the skin, convulsions, dilated pupils, inactivity, lack of coordination, paralysis, redness in the arms and legs, skin changes at the site of injection, slow breathing, sluggishness, tremor