Isordil

Recommended dosage

Because you can develop a tolerance to this drug, your doctor may schedule a daily period of time when you do not take any drug.

ADULTS

The usual sublingual starting dose for the treatment of angina pectoris is 2.5 milligrams to 5 milligrams. Your doctor will increase this initial dose gradually until the pain subsides or side effects prove bothersome.

The usual sublingual starting dose for the prevention of an impending attack of angina pectoris is usually 5 or 10 milligrams every 2 to 3 hours.

To prevent chronic stable angina pectoris, the usual starting dose for swallowed, immediately released Isordil is 5 to 20 milligrams. Your doctor may increase this initial dose to 10 to 40 milligrams every 6 hours.

To prevent chronic stable angina pectoris with controlled-release Isordil, the usual initial dose is 40 milligrams. Your doctor may increase this dose from 40 to 80 milligrams given every 8 to 12 hours.

CHILDREN

The safety and effectiveness of Isordil have not been established for children.

Overdosage

Any medication taken in excess can have serious consequences. Severe overdosage of Isordil can be fatal. If you suspect an overdose, seek medical help immediately.

• Symptoms of Isordil overdose may include:
  Bloody diarrhea, coma, confusion, convulsions, fainting, fever, flushed and perspiring skin (later cold and blue), nausea, palpitations, paralysis, rapid decrease in blood pressure, rapid, then difficult and slow breathing, slow pulse, throbbing headache, vertigo, visual disturbances, vomiting