Lexxel

Pronounced: LECKS-ell
Generic ingredients: Enalapril maleate, Felodipine

Why is Lexxel prescribed?

Lexxel is used to treat high blood pressure. It combines two blood pressure drugs: an ACE inhibitor and a calcium channel blocker. The ACE inhibitor (enalapril) lowers blood pressure by preventing a chemical in your blood called angiotensin I from converting to a more potent form that narrows the blood vessels and increases salt and water retention. The calcium channel blocker (felodipine) also works to keep the blood vessels open, and eases the heart's workload by reducing the force and rate of your heartbeat.

Lexxel can be prescribed alone or in combination with other blood pressure medicines, especially water pills (diuretics) such as HydroDIURIL or Esidrix.

Most important fact about Lexxel

Doctors usually prescribe Lexxel for patients who have been taking one of its components--enalapril (Vasotec) or extended-release felodipine (Plendil)--without showing improvement. Like other blood pressure medications, Lexxel must be taken regularly for it to be effective. Since blood pressure declines gradually, it may be 1 or 2 weeks before you get the full benefit of Lexxel; and you must continue taking it even if you are feeling well. Lexxel does not cure high blood pressure; it merely keeps it under control.

How should you take Lexxel?

Lexxel can be taken with a light meal or without food. Remember, however, that a high-fat meal can reduce its effectiveness, and that grapefruit juice increases its impact.

Swallow Lexxel tablets whole. Do not crush, divide, or chew them.

--If you miss a dose...

Take it as soon as you remember. If it is almost time for your next dose, skip the one you missed and go back to your regular schedule. Never take 2 doses at the same time.

--Storage instructions...

Store at room temperature. Keep the container tightly closed and protect from light and humidity.

What side effects may occur?

Side effects cannot be anticipated. If any develop or change in intensity, inform your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking Lexxel.

• More common side effects may include:
  Dizziness, headache, swelling