Lexapro

In rare cases, Lexapro can trigger mania (unreasonably high spirits and excess energy). If you've ever had this problem, be sure to let the doctor know.

Also make sure that the doctor knows if you have liver problems or severe kidney disease. Your dosage may need adjustment.

Convulsions have been reported during Lexapro treatment. If you have a history of seizures, use this drug with caution.

Serotonin-boosting antidepressants could potentially cause stomach bleeding, especially in older people or those taking nonsteroidal anti-inflammatory drugs (NSAIDs) such as aspirin, ibuprofen (Advil, Motrin), naproxen (Aleve), and ketoprofen (Orudis KT). Consult your doctor before combining Lexapro with NSAIDs or blood-thinning medications.

You should never stop taking Lexapro without consulting your doctor. An abrupt decrease in dose could cause withdrawal symptoms such as mood problems, lethargy, insomnia, and tingling sensations.

Possible food and drug interactions when taking Lexapro

Do not use Lexapro if you are taking the related drug Celexa. Be sure to avoid MAO inhibitors when taking Lexapro. Although Lexapro does not interact with alcohol, the manufacturer recommends avoiding alcoholic beverages.

If Lexapro is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Lexapro with the following:

Aspirin
Carbamazepine (Tegretol)
Cimetidine (Tagamet)
Desipramine (Norpramin)
Drugs that act on the brain, including antidepressants, painkillers, sedatives, and tranquilizers
Ketoconazole (Nizoral)
Linezolid (Zyvox)
Lithium (Eskalith)
Metoprolol (Lopressor)
Narcotic painkillers
Nonsteroidal anti-inflammatory drugs such as Advil and Motrin
Sumatriptan (Imitrex)
Warfarin (Coumadin)

Special information if you are pregnant or breastfeeding

There have been reports of newborns developing serious complications after exposure to Lexapro late in the last 3 months of pregnancy. If you are pregnant or plan to become pregnant, inform your doctor immediately. Lexapro should be taken during pregnancy only if its benefits outweigh the potential risks.

Lexapro appears in breast milk and can affect a nursing infant. If you decide to breastfeed, Lexapro is not recommended.