Lodine

Special warnings about Lodine

Peptic ulcers and bleeding can occur without warning. You may have other problems with bleeding as well.

Call your doctor if you have any signs or symptoms of stomach or intestinal ulcers or bleeding, blurred vision or other eye problems, skin rash, weight gain, or fluid retention and swelling.

This drug should be used with caution if you have kidney or liver disease; and it can cause liver inflammation in some people.

Do not take aspirin or any other anti-inflammatory medications while taking Lodine, unless your doctor tells you to do so.

If you are taking Lodine over an extended period of time, your doctor should check your blood for anemia.

This drug can increase water retention. Use with caution if you have heart disease or high blood pressure.

Possible food and drug interactions when taking Lodine

If Lodine is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Lodine with the following:

Aspirin
Cyclosporine (Sandimmune, Neoral)
Digoxin (Lanoxin)
Lithium (Lithobid, others)
Methotrexate
Phenylbutazone (Butazolidin)
The blood-thinning drug warfarin (Coumadin)

Special information if you are pregnant or breastfeeding

The effects of Lodine during pregnancy have not been adequately studied. However, you should definitely not take it in late pregnancy. If you are pregnant or plan to become pregnant, inform your doctor immediately. Lodine may appear in breast milk and could affect a nursing infant. If this medication is essential to your health, your doctor may advise you to discontinue breastfeeding until your treatment with this medication is finished.

Recommended dosage

ADULTS

General Pain Relief

Take 200 to 400 milligrams every 6 to 8 hours as needed. Ordinarily, you should not take more than 1,000 milligrams a day, although your doctor may increase the dose to 1,200 milligrams a day if absolutely necessary.

Osteoarthritis and Rheumatoid Arthritis