Lotrel

Pronounced: LOW-trel
Generic names: Amlodipine and Benazepril Hydrochloride

Why is Lotrel prescribed?

Lotrel is used in the treatment of high blood pressure. It is a combination medicine that is used when treatment with a single drug has not been successful or has caused side effects.

One component, amlodipine, is a calcium channel blocker. It eases the workload of the heart by slowing down the passage of nerve impulses and hence the contractions of the heart muscle. This improves blood flow through the heart and throughout the body and reduces blood pressure. The other component, benazepril, is an angiotensin-converting enzyme (ACE) inhibitor. It works by preventing the transformation of a hormone called angiotensin I into a more potent substance that increases salt and water retention in your body.

Most important fact about Lotrel

You must take Lotrel regularly for it to be effective. Since blood pressure declines gradually, it may take 1 to 2 weeks for the full effect of Lotrel to be seen. Even if you are feeling well, you must continue to take the medication. Lotrel does not cure high blood pressure; it merely keeps it under control.

How should you take Lotrel?

Take Lotrel exactly as prescribed by your doctor. Try to take your medication at the same time each day, such as before or after breakfast, so that it is easier to remember.

--If you miss a dose...

Take it as soon as you remember. However, if it is almost time for your next dose, skip the one you missed and go back to your regular schedule. Do not take 2 doses at once.

--Storage instructions...

Store at room temperature. Store away from moisture and light; avoid excessive heat.

What side effects may occur?

Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking Lotrel.

If you develop swelling of your face, around the lips, tongue, or throat; swelling of arms and legs; or difficulty swallowing, you should contact your doctor immediately. You may need emergency treatment. Be especially wary if you're an African American: Your chances of this type of reaction are higher. Severe allergic reactions are also more likely if you are being given bee or wasp venom to guard against future reactions to stings.