Lotrel

If Lotrel is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Lotrel with the following:

• Lithium
• Potassium supplements
• Potassium-sparing diuretics such as amiloride, spironolactone, and triamterene
• Diuretics such as chlorothiazide, furosemide, hydrochlorothiazide

Special information if you are pregnant or breastfeeding

Lotrel can cause injury or death to developing and newborn babies, especially if taken during the second and third trimesters of pregnancy. If you are pregnant and are taking Lotrel, contact your doctor immediately to discuss the potential hazard to your unborn child. Minimal amounts of benazepril appear in breast milk. If this medication is essential to your health, your doctor may advise you to discontinue breastfeeding while you are taking Lotrel.

Recommended dosage for Lotrel

ADULTS

Your doctor will closely monitor the effects of this drug and adjust the dosage according to your blood pressure response. Lotrel is available in capsules that contain 2.5 milligrams of amlodipine and 10 milligrams of benazepril, capsules containing 5 milligrams of amlodipine and 10 or 20 milligrams of benazepril and capsules containing 10 milligrams of amlodipine and 20 milligrams of benazepril. Small, older, frail, and kidney- or liver-impaired individuals usually start with the lowest dose.

CHILDREN

Safety and effectiveness in children have not been established.

Overdosage

Any medication taken in excess can have serious consequences. Although there is no specific information available, a sudden drop in blood pressure and rapid heartbeat would be the primary symptoms of a Lotrel overdose. If you suspect an overdose, seek medical attention immediately.