Macrodantin

--If you miss a dose...

Take the forgotten dose as soon as you remember, then space out the rest of the day's doses at equal intervals.

--Storage instructions...

Store at room temperature. Protect from light and keep the container tightly closed.

What side effects may occur?

Side effects cannot be anticipated. If any develop or change in intensity, inform your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking nitrofurantoin.

• More common side effects may include:
  Lack or loss of appetite, nausea, vomiting

Why should Macrodantin not be prescribed?

If you are sensitive to or have ever had an allergic reaction to nitrofurantoin or other drugs of this type, such as Furoxone, you should not take this medication. Make sure that your doctor is aware of any drug reactions that you have experienced.

Unless you are directed to do so by your doctor, do not take this medication if you have poor kidneys, producing little or no urine.

Nitrofurantoin should not be taken at term of pregnancy or during labor and delivery; it should not be given to infants under 1 month of age.

Special warnings about Macrodantin

Tell your doctor if you have any unusual symptoms while you are taking this drug.

Fatalities have been reported from hepatitis (liver disease) during treatment with nitrofurantoin. Long-lasting, active hepatitis can develop without symptoms; therefore, if you are receiving long-term treatment with this drug, your doctor should test your liver function periodically.

Fatalities from peripheral neuropathy--a disease of the nerves--have also been reported in people taking nitrofurantoin. Conditions such as a kidney disorder, anemia, diabetes mellitus, a debilitating disease, or a vitamin B deficiency make peripheral neuropathy more likely. If you develop symptoms such as muscle weakness or lack of sensation, check with your doctor immediately.

If you experience diarrhea, tell your doctor. It may be a sign of serious intestinal inflammation.

Hemolytic anemia (destruction of red blood cells) has occurred in people taking nitrofurantoin.