Mirapex

Why should Mirapex not be prescribed?

If Mirapex gives you an allergic reaction, you'll be unable to use it.

Special warnings about Mirapex

Mirapex can cause your blood pressure to drop when you first stand up, resulting in symptoms such as dizziness, nausea, fainting, blackouts, and, sometimes, sweating. To avoid or reduce these symptoms, try to stand up slowly, especially at the beginning of treatment with Mirapex.

Mirapex can cause drowsiness and may trigger hallucinations, especially if you are over 65 or have an advanced case of Parkinson's. You may even fall asleep--without warning and without feeling drowsy--while performing everyday activities. Check with your doctor immediately if you find that you're getting drowsy or falling asleep while eating, talking, or watching television. Do not drive a car or undertake other dangerous activities until you've spoken with the doctor. Be especially cautious when taking other drugs that cause sleepiness.

If you have a kidney condition, make sure the doctor is aware of it. You'll probably need regular blood tests to check your kidney function, and your dosage of Mirapex may have to be reduced.

In very rare cases, Mirapex may cause muscle wasting. If you develop muscle aches or soreness after you start Mirapex, be sure to tell your doctor. Also alert your doctor if you notice any changes in your eyesight.

Possible food and drug interactions when taking Mirapex

If Mirapex is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Mirapex with the following:

Carbidopa/Levodopa (Sinemet)
Sedatives and tranquilizers such as chloral hydrate, codeine products, Dalmane, Halcion, and phenobarbital
Cimetidine (Tagamet)
Diltiazem (Cardizem, Dilacor XR)
Major tranquilizers such as Compazine, Haldol, Mellaril, Navane, Prolixin, Stelazine, and Thorazine
Metoclopramide (Reglan)
Quinidine (Quinidex, Quinaglute)
Quinine
Ranitidine (Zantac)
Triamterene (Dyrenium)
Verapamil (Calan, Isoptin)

Combining Mirapex with Sinemet or Larodopa sometimes triggers twitching and jerky movements. If this happens, tell your doctor. A reduction in your dose of Sinemet or Larodopa may solve the problem.