Niaspan

Pronounced: NYE-uh-span
Generic name: Niacin

Why is Niaspan prescribed?

Although the niacin in Niaspan is one of the B-complex vitamins, this drug isn't taken to prevent deficiencies. In large doses, niacin also lowers cholesterol, and Niaspan extended-release tablets are designed specifically for this purpose.

Excessive levels of cholesterol in the blood can lead to clogged arteries and increased risk of heart attack. Niaspan is prescribed, along with a low-fat, low cholesterol diet, to reduce blood cholesterol levels, combat clogged arteries, and lower the chance of repeated heart attacks. It is used only when diet alone fails to do the job, and is often taken along with another type of cholesterol-lowering drug known as a bile acid sequestrant (Colestid, Questran, WelChol). It can also be combined with any of the cholesterol-lowering "statin" drugs (Lescol, Lipitor, Mevacor, Pravachol, Zocor).

Niaspan is also used to reduce very high levels of the blood fats known as triglycerides, a condition that can cause painful inflammation of the pancreas.

Most important fact about Niaspan

Before starting therapy with Niaspan, your doctor will try to control your cholesterol and triglyceride (fat) levels with a diet low in cholesterol and saturated fat, as well as a program of exercise and, if necessary, weight reduction. It's important to remember that Niaspan (like other cholesterol-lowering drugs) is a supplement--not a substitute--for these measures. To get the most from Niaspan, you need to continue the diet and exercise program prescribed by your doctor.

How should you take Niaspan?

Take this medication exactly as prescribed by your doctor. To minimize the "flushing" effect of Niaspan, your doctor may ask you to take aspirin or a nonsteroidal anti-inflammatory medication (NSAID) such as Motrin or Aleve 30 minutes before taking Niaspan.

Niaspan is taken once a day at bedtime after a low-fat snack. Do not take Niaspan on an empty stomach. If flushing wakes you up during the night, get up slowly, especially if you feel dizzy or faint, or if you are also taking blood pressure medicine.