Noroxin

• Side effects may include:
  Abdominal cramping, dizziness, headache, nausea, weakness

Why should Noroxin not be prescribed?

You should not be using Noroxin if you are sensitive to it or to other drugs of the same type, such as ciprofloxacin, or if you have suffered tendon inflammation or tearing due to the use of such drugs. See "Special Warnings" section.

Special warnings about Noroxin

Noroxin is not recommended for:

• Children (under the age of 18)
• Nursing mothers
• Pregnant women

People with disorders such as epilepsy, severe cerebral arteriosclerosis, and other conditions that might lead to seizures should use Noroxin cautiously. There have been reports of convulsions in some people taking Noroxin.

Use Noroxin with caution if you suffer from the disease Myasthenia gravis. Noroxin may cause life-threatening respiratory problems under these circumstances.

If you develop diarrhea, tell your doctor. It could be a symptom of a potentially serious intestinal inflammation.

Some people taking drugs chemically similar to Noroxin have experienced severe, sometimes fatal reactions, occasionally after only one dose. These reactions may include: Confusion, convulsions, difficulty breathing, hallucinations, heart collapse, hives, increased pressure in the head, itching, light-headedness, loss of consciousness, psychosis, rash, restlessness, shock, swelling in the face or throat, tingling, tremors.

If you experience any of these reactions you should immediately stop taking Noroxin and seek medical help.

There is a small chance that Noroxin may weaken the muscle tendons in your shoulder, hand, or heel, causing them to tear. Should this happen, surgery or at least a long period of disability would be in store. If you feel any pain, inflammation, or tearing, stop taking this drug immediately and call your doctor. Rest and avoid exercise until the doctor is certain the tendons are intact.

In rare cases, people taking Noroxin have developed an irregular hearbeat. Although it is unknown if Noroxin was definitely the cause, you should still use the drug with caution if you have low potassium levels, a slow heartbeat, or take drugs to control your heartbeat.

Some people find needle-shaped crystals in their urine after taking Noroxin. Drink plenty of fluids while taking Noroxin. This will increase urine output and reduce crystallization.

Noroxin may cause dizziness or light-headedness and might impair your ability to drive a car or operate potentially dangerous machinery. Use caution when undertaking any activities that require full alertness if you are unsure of your ability.

You should avoid excessive exposure to direct sunlight while taking Noroxin. Stop taking Noroxin and contact your doctor immediately if you have a severe reaction to sunlight, such as a skin rash.

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Possible food and drug interactions when taking Noroxin

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If Noroxin is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Noroxin with the following:

• Antacids
• Caffeine (including coffee, tea, and some soft drinks)
• Calcium supplements
• Cyclosporine
• Didanosine
• Glyburide
• Multivitamins and other products containing iron or zinc
• Nitrofurantoin
• Oral blood thinners such as warfarin
• Probenecid
• Sucralfate
• Theophylline

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Special information if you are pregnant or breastfeeding

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The effects of Noroxin during pregnancy have not been adequately studied. Inform your doctor if you are pregnant or planning a pregnancy.

Do not take Noroxin while breastfeeding. There is a possibility of harm to the infant.

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Recommended dosage for Noroxin

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Take Noroxin with a full glass of water 1 hour before, or 2 hours after, eating a meal or drinking milk. Drink plenty of liquids while taking Noroxin.

The elderly and people with kidney problems may need to use a reduced dosage or have their kidney function monitored.

Uncomplicated Urinary Tract Infections

The suggested dose is 800 milligrams per day; 400 milligrams should be taken twice a day for 3 to 10 days, depending upon the kind of bacteria causing the infection. People with impaired kidney function may take 400 milligrams once a day for 3 to 10 days.

Complicated Urinary Tract Infections

The suggested dose is 800 milligrams per day; 400 milligrams should be taken twice a day for 10 to 21 days.

Prostatitis

The usual daily dose is 800 milligrams, divided into 2 doses of 400 milligrams each, taken for 28 days.

Sexually Transmitted Diseases (Gonorrhea)

The usual recommended dose is one single dose of 800 milligrams for 1 day.

The total daily dosage of Noroxin should not be more than 800 milligrams.

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Overdosage

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The symptoms of overdose with Noroxin are not known. However, any medication taken in excess can have serious consequences. If you suspect a Noroxin overdose, seek medical help immediately.