Norpramin

Why should Norpramin not be prescribed?

Norpramin should not be used if you are known to be hypersensitive to it, or if you have had a recent heart attack.

People who take antidepressant drugs known as MAO inhibitors (including Nardil and Parnate) should not take Norpramin.

Special warnings about Norpramin

In clinical studies, antidepressants increased the risk of suicidal thinking and behavior in children and adolescents with depression and other psychiatric disorders. Anyone considering the use of Norpramin or any other antidepressant in a child or adolescent must balance this risk with the clinical need. Norpramin has not been studied in children.

Additionally, the progression of major depression is associated with a worsening of symptoms and/or the emergence of suicidal thinking or behavior in both adults and children, whether or not they are taking antidepressants. Individuals being treated with Norpramin and their caregivers should watch for any change in symptoms or any new symptoms that appear suddenly--especially agitation, anxiety, hostility, panic, restlessness, extreme hyperactivity, and suicidal thinking or behavior--and report them to the doctor immediately. Be especially observant at the beginning of treatment or whenever there is a change in dose.

Before using Norpramin, tell your doctor if you have heart or thyroid disease, a seizure disorder, a history of being unable to urinate, or glaucoma.

Nausea, headache, and uneasiness can result if you suddenly stop taking Norpramin. Consult your doctor and follow instructions closely when discontinuing Norpramin.

This drug may impair your ability to drive a car or operate potentially dangerous machinery. Do not participate in any activities that require full alertness if you are unsure about your ability.

Norpramin may increase your skin's sensitivity to sunlight. Overexposure could cause rash, itching, redness, or sunburn. Avoid direct sunlight or wear protective clothing.

If you are planning to have elective surgery, make sure that your doctor is aware that you are taking Norpramin. It should be discontinued as soon as possible prior to surgery.