Parnate
Also see more information on Parnate Oral from the
First Databank
drug library.
Brand name:
Parnate
Pronounced: PAR-nate
Generic name: Tranylcypromine sulfate
Why is Parnate prescribed?
Parnate is prescribed for the treatment of major
depression--that is, a depressed mood that lasts for at least 2
weeks and interferes with daily functioning. Major depression is
marked by at least 4 of the following 8 symptoms: changes in
appetite, changes in sleep patterns, agitation or listlessness,
loss of interest in usual activities or a decrease in sex drive,
fatigue, feelings of guilt or worthlessness, slowed thinking or
difficulty concentrating, and thoughts of suicide.
Parnate is a member of the class of drugs known as monoamine
oxidase (MAO) inhibitors. It works by increasing concentrations of
the brain chemicals epinephrine, norepinephrine, and serotonin.
Most important fact about Parnate
Parnate is a potent drug with the capability of producing
serious side effects. It is typically prescribed only if other
antidepressants fail, and then only for adults who are under close
medical supervision. It is considered especially risky because it
can interact with a long list of drugs and foods to produce
life-threatening side effects (see "Possible food and drug
interactions when taking this medication").
How should you take Parnate?
Your doctor will adjust the dosage of Parnate according to your
individual needs and response. The drug usually produces
improvement within 48 hours to 3 weeks after starting therapy.
--If you miss a dose...
Take it as soon as you remember. If it is within 2 hours of your
next dose, skip the one you missed and go back to your regular
schedule. Never take 2 doses at once.
--Storage instructions...
Store at room temperature.
What side effects may occur?
Side effects cannot be anticipated. If any develop or change in
intensity, inform your doctor as soon as possible. Only your doctor
can determine if it is safe for you to continue taking Parnate.
-
More common side effects may include:
Blood disorders, diarrhea, dizziness, drowsiness, dry
mouth, insomnia, muscle spasm, nausea, overstimulation, rapid or
irregular heartbeat, restlessness, ringing in the ears, water
retention, weakness, weight loss
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Also see more information on Parnate Oral from the
First Databank
drug library.
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