Parnate
Overview
- About Parnate
If you have kidney problems, make sure the doctor is aware of this. The doctor may need to reduce your dosage of Parnate to avoid a buildup of the drug. Parnate should also be used with caution if you have an overactive thyroid gland.
MAO inhibitors can suppress heart pain that would otherwise serve as a warning sign of a heart attack. For this reason and others, it should be used with caution by older adults. Also, it should be used with caution by diabetics and people with epilepsy or other convulsive disorders because it can alter the level of drugs used to treat these conditions. Tell every doctor or dentist who you see that you are taking Parnate.
Possible food and drug interactions when taking Parnate
Return to topNever take Parnate with the following drugs; the combination can trigger seizures or a dangerous spike in blood pressure:
- Other MAO inhibitors such as phenelzine
- Antidepressant drugs classified as tricyclics, such as amitriptyline, clomipramine, and imipramine
- Carbamazepine
- Cyclobenzaprine
- Antidepressant drugs classified as selective serotonin reuptake inhibitors, such as fluoxetine, paroxetine, and sertraline
- Amphetamines such as dextroamphetamine
- Anesthetics
- Antihistamines such as desloratadine, diphenhydramine, and fexofenadine
- Blood pressure medications such as benazepril, lisinopril, and quinapril
- Bupropion
- Buspirone
- Cold and hay fever remedies that constrict blood vessels
- Cough remedies containing dextromethorphan
- Demerol and other narcotic painkillers such as hydrocodone and oxycodone
- Disulfiram
- Guanethidine
- Methyldopa
- Over-the-counter weight reduction aids
- Parkinson's disease medications such as bromocriptine, ropinirole, and levodopa
- Reserpine
- Sedatives such as pentobarbital, secobarbital, and triazolam
- Tryptophan
- Water pills such as hydrochlorothiazide
- Anchovies
- Avocados
- Bananas
- Beer (including nonalcoholic beer)
- Caviar
- Cheese (especially strong and aged varieties)
- Chianti wine
- Chocolate
- Dried fruits (including raisins, prunes, and figs)
- Liqueurs
- Liver
- Meat extracts or meat prepared with tenderizers
- Overripe fruit
- Pickled herring
- Pods of broad beans like fava beans
- Raspberries
- Sauerkraut
- Sherry
- Sour cream
- Soy sauce
- Yeast extracts
- Yogurt
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Symptoms of Parnate overdose may include:
Agitation, confusion, coma, dizziness, drowsiness, high fever, incoherence, rigid muscles, severe headache, twitching, weakness
When switching from one of these drugs to Parnate, or vice versa, allow an interval of at least 1 week between medications.
Also avoid combining Parnate with any of the following:
While taking Parnate, you should also avoid foods that contain a high amount of a substance called tyramine, including:
Likewise, avoid alcohol and large amounts of caffeine.
Special information if you are pregnant or breastfeeding
Return to topIf you are pregnant or plan to become pregnant, inform your doctor immediately. Parnate should be used during pregnancy only if its benefits outweigh potential risks.
Parnate makes its way into breast milk. If the drug is essential to your health, your doctor may advise you to stop nursing until your treatment is finished.
Recommended dosage for Parnate
Return to topADULTS
The usual dosage is 30 milligrams per day, divided into smaller doses. If ineffective, the dosage may be slowly increased under your doctor's supervision to a maximum of 60 milligrams per day.
Overdosage
Return to topAny medication taken in excess can have serious consequences. If you suspect an overdose of Parnate, seek medical help immediately.
