Peganone

Why should Peganone not be prescribed?

Do not take Peganone if you have liver problems or blood disorders.

Special warnings about Peganone

Blood abnormalities have occurred in some patients taking Peganone, although it is unknown whether the drug was the cause. Your doctor will do monthly blood tests when you first start therapy to guard against any such problems. Call your doctor immediately if you have symptoms such as sore throat, fever, malaise (marked by bodily discomfort, fatigue, or a general feeling of illness), easy bruising, small purple skin spots, nosebleeds, or any sign of infection or bleeding tendency.

The doctor may also check your liver function if he or she suspects a problem.

There is some evidence that Peganone may interfere with the body's metabolism of folic acid, which could lead to anemia. Talk to your doctor about taking supplements, especially if you're planning to become pregnant.

If you have systemic lupus erythematosus, you should be aware that Peganone could make the symptoms worse.

Because Peganone may cause gum hypertrophy (excessive formation of the gums over the teeth), it's important to practice good dental hygiene while taking this drug.

Possible food and drug interactions when taking Peganone

If Peganone is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Peganone with the following:

• Blood-thinning drugs such as warfarin
• Drugs used to treat blood disorders
• Phenacemide

Although no specific problems with alcohol have been reported, it's still a good idea to watch your alcohol intake while taking this drug.

Special information if you are pregnant or breastfeeding

If you are pregnant or plan to become pregnant, inform your doctor immediately. Because of the possibility of birth defects with antiepileptic drugs such as Peganone, you may need to discontinue the drug. Do not, however, stop taking it without first consulting your doctor. Because Peganone appears in breast milk, you should not breastfeed during treatment with the drug.