Periactin

Older people, in particular, are likely to become dizzy or drowsy, or develop low blood pressure in response to Periactin.

Why should Periactin not be prescribed?

Do not take Periactin if you are sensitive to it, or have ever had an allergic reaction to it or to a similar antihistamine.

Do not take Periactin if you are taking an antidepressant drug known as an MAO inhibitor. Drugs in this category include Nardil and Parnate.

Do not take Periactin if you have the eye condition called angle-closure glaucoma, a peptic ulcer, an enlarged prostate, obstruction of the neck of the bladder, or obstruction of the outlet of the stomach.

Newborn or premature infants should not be given this drug, nor should it be used by women who are breastfeeding an infant.

The elderly and those in a weakened condition should not take this drug.

Special warnings about Periactin

Like other antihistamines, Periactin may make you drowsy or impair your coordination. Be very careful about driving, climbing, or operating machinery, or doing hazardous tasks until you know how you react to this medication.

Be cautious about taking Periactin if you have bronchial asthma, the eye condition called glaucoma, an overactive thyroid gland, high blood pressure, heart disease, or circulatory problems.

Possible food and drug interactions when taking Periactin

Avoid alcoholic beverages while taking Periactin.

If Periactin is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Periactin with the following:

Antidepressant drugs classified as MAO inhibitors, including Nardil and Parnate
Sedatives such as Nembutal and Seconal
Tranquilizers such as Librium and Valium

Special information if you are pregnant or breastfeeding

Because of possible harm to the unborn baby, Periactin should not be used during pregnancy unless it is clearly needed. Periactin should not be taken by a woman who is breastfeeding. If you have just given birth, you will need to choose between breastfeeding and taking Periactin.