Plaquenil

The usual starting dose for adults is 400 milligrams once or twice daily. You will continue to take this dose for several weeks or months, depending on your response. For longer-term maintenance therapy, your doctor may reduce the dose to 200 to 400 milligrams per day.

Rheumatoid Arthritis

The usual starting dose for adults is 400 to 600 milligrams a day taken with a meal or a glass of milk. If your condition improves, usually within 4 to 12 weeks, your doctor will reduce the dose to a maintenance level of 200 to 400 milligrams daily.

CHILDREN

For the treatment of malaria, your doctor will calculate the dosage on the basis of your child's weight.

This drug has not been proved safe for treatment of juvenile arthritis.

Overdosage

Any medication taken in excess can have serious consequences. If you suspect an overdose, seek emergency medical treatment immediately.

• Symptoms of an overdose of Plaquenil may occur within 30 minutes. They include:
  Convulsions, drowsiness, headache, heart problems and failure, inability to breathe, visual problems