Premarin
Also see more information on Premarin Oral from the
First Databank
drug library.
Brand name:
Premarin
Pronounced: PREM-uh-rin
Generic name: Conjugated estrogens
Other brand names: Cenestin, Premphase, Prempro
Why is Premarin prescribed?
Premarin is an estrogen replacement drug. The tablets are used
to reduce moderate to severe symptoms of menopause, including
feelings of warmth in the face, neck, and chest, and the sudden
intense episodes of heat and sweating known as "hot flashes."
Cenestin tablets, containing a synthetic form of conjugated
estrogens, may also be prescribed for these symptoms.
In addition to the symptoms of menopause, Premarin tablets are
prescribed for teenagers who fail to mature at the usual rate, and
to relieve the symptoms of certain types of cancer, including some
forms of breast and prostate cancer.
In addition, either the tablets or Premarin vaginal cream can be
used for other conditions caused by lack of estrogen, such as dry,
itchy external genitals and vaginal irritation.
Along with diet, calcium supplements, and exercise, Premarin
tablets are also prescribed to prevent postmenopausal osteoporosis,
a condition in which the bones become brittle and easily broken.
Before taking Premarin solely for this purpose, you should
carefully consider using alternative, nonestrogen therapies.
The addition of progesterone to estrogen-replacement therapy has
been shown to reduce the risk of uterine cancer. Prempro combines
estrogen and progesterone in a single tablet taken once daily.
Premphase is a 28-day supply of tablets. The first 14 contain only
estrogen. The second 14 supply both estrogen and progesterone. Both
Prempro and Premphase are prescribed to reduce the symptoms of
menopause, including vaginal problems, and to prevent
osteoporosis.
Most important fact about Premarin
Because estrogens have been linked with an increased risk of
uterine and endometrial cancer (cancer in the lining of the
uterus), it is essential to have regular checkups and to report any
unusual vaginal bleeding to your doctor immediately.
Premarin and other estrogen drugs, with or without progesterone,
should not be used to prevent heart disease. Recent studies have
confirmed an increased rate of heart attack, stroke, and dangerous
blood clots among women taking estrogen or estrogen combinations
for 5 years. Blood clots can lead to phlebitis, stroke, heart
attack, a loss of blood supply to the lungs, a blockage in the
blood vessels serving the eye, and other serious disorders.
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Also see more information on Premarin Oral from the
First Databank
drug library.
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