Sandimmune

Special information if you are pregnant or breastfeeding

The effects of Sandimmune in pregnancy have not been adequately studied. If you are pregnant or plan to become pregnant, inform your doctor immediately. Sandimmune should be used during pregnancy only if the benefit justifies the potential risk to the unborn child. Since Sandimmune appears in breast milk, it should not be used during breastfeeding. If you are a new mother, you may need to choose between taking Sandimmune and breastfeeding your baby.

Recommended dosage for Sandimmune

ADULTS

Transplant Rejection

Your doctor will tailor your dosage of Sandimmune in accordance with your body's response. Expect a single dose of 15 milligrams per 2.2 pounds of body weight 4 to 12 hours before a transplant and 1 dose daily for 1 to 2 weeks after the operation. After that, the doctor may keep you on a daily dose of 5 to 10 milligrams per 2.2 pounds of body weight.

The dosage of Neoral depends on the type of transplant and the other drugs you are taking. It is always taken twice a day.

Psoriasis or Rheumatoid Arthritis

The starting dosage is 2.5 milligrams of Neoral per 2.2 pounds of body weight divided into 2 doses per day. Your doctor may gradually increase the daily dose to a maximum of 4 milligrams per 2.2 pounds.

CHILDREN

Dosage is generally the same for children as for adults, though somewhat higher doses are sometimes needed. Both drugs have been used to prevent transplant rejection in small children. Neoral has not been tested for arthritis or psoriasis in children under 18.

Overdosage

Although no specific information is available, an overdose of Sandimmune would be expected to cause liver and kidney problems. Any medication taken in excess can have serious consequences. If you suspect an overdose of Sandimmune, seek medical attention immediately.