Semprex-D

Do not take this drug within 14 days of taking any drug known as an MAO inhibitor, including the antidepressants Nardil and Parnate.

Special warnings about Semprex-D

Use this drug with caution if you have high blood pressure, diabetes, heart problems, peptic ulcer or other stomach problems, or an enlarged prostate gland. Use Semprex-D with care, too, if you have increased eye pressure, an overactive thyroid gland, or kidney disease. Make sure the doctor has taken these conditions into account.

Antihistamines are more likely to cause dizziness, extreme calm (sedation), bladder obstruction, and low blood pressure in the elderly (over age 60). The elderly are also more likely to have more side effects from the decongestant (pseudoephedrine) in Semprex-D.

Possible food and drug interactions when taking Semprex-D

If Semprex-D is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining this drug with the following:

Alcoholic beverages
Blood pressure medications such as Inderal and Lopressor
MAO inhibitors, including the antidepressants Nardil and Parnate
Other antihistamines such as Actifed, Seldane-D, and Entex
Other decongestants such as Quibron and Rynatan

Special information if you are pregnant or breastfeeding

The effects of Semprex-D during pregnancy have not been adequately studied. If you are pregnant or plan to become pregnant, tell your doctor immediately.

It is not known whether acrivastine appears in breast milk, but pseudoephedrine does. If the drug is essential to your health, your doctor may tell you to stop nursing until your treatment is finished.

Recommended dosage

ADULTS

The usual dose for adults and children 12 years of age and older is 1 capsule, taken by mouth, every 4 to 6 hours, 4 times a day.

CHILDREN

The safety and effectiveness of Semprex-D in children less than 12 years old have not been established.

Overdosage

Although there have been few reports of overdosage with Semprex-D, overdosage with similar drugs has caused a variety of serious symptoms. If you suspect an overdose of Semprex-D, seek medical attention immediately.

• Symptoms of overdose may include:
  Anxiety, convulsions, difficult breathing, drowsiness, fear, hallucinations, heart failure with low blood pressure, irregular heartbeat, loss of consciousness, painful urination, paleness, restlessness, sleeplessness, tenseness, trembling, weakness