Seroquel

Generic name: Quetiapine fumarate

Why is Seroquel prescribed?

Seroquel is prescribed for the treatment of schizophrenia, a mental disorder marked by delusions (false beliefs), hallucinations, disrupted thinking, and loss of contact with reality. It is also used for the treatment of manic and depressive episodes associated with bipolar disorder.

Seroquel belongs to one of the newer classes of antipsychotic medications. Researchers believe that it works by diminishing the action of dopamine and serotonin, two of the brain's chief chemical messengers.

Most important fact about Seroquel

Seroquel may cause tardive dyskinesia, a condition characterized by uncontrollable muscle spasms and twitches in the face and body. This problem can be permanent, and appears to be most common among older adults, especially women.

Seroquel is not approved for use in elderly patients with dementia (including Alzheimer's disease) due to the increased risk of sudden death, heart failure, and pneumonia.

Antidepressants can increase the risk of suicidal thinking and behavior in children and teenagers. Both adult and pediatric patients taking antidepressants should be watched closely for changes in moods or actions, especially when they first start therapy or when their dose is increased or decreased. Patients and their families should contact the doctor immediately if new symptoms develop or seem to get worse. Signs to watch for include anxiety, hostility, insomnia, restlessness, impulsive or dangerous behavior, and thoughts about suicide or dying. Seroquel is not approved for use in pediatric patients.

How should you take Seroquel?

Your doctor will increase your dose gradually until the drug takes effect. If you stop Seroquel for more than 1 week, you'll need to build up to your ideal dosage once again.

• If you miss a dose...
  Take it as soon as you remember. If it is almost time for the next dose, skip the one you missed and go back to your regular schedule. Do not take 2 doses at once.