Seroquel
Overview
- About Seroquel
Special information if you are pregnant or breastfeeding
Return to topThe possibility of harm to a developing baby has not been ruled out. You should take Seroquel during pregnancy only if the benefits outweigh this potential risk. Notify your doctor as soon as you become pregnant or decide to become pregnant.
It is not known whether Seroquel appears in breast milk, and breastfeeding is not recommended.
Recommended dosage for Seroquel
Return to topSCHIZOPHRENIA
Adults
The usual dosage range is 300 to 400 milligrams a day, divided into two or three smaller doses. Doses as low as 150 milligrams a day sometimes prove effective, and the dose rarely exceeds 750 milligrams per day. Doses above 800 milligrams per day have not been tested for safety. The dose is gradually increased over 4 days until the most effective dose is reached, using the following schedule: Day 1: Take 25 milligrams twice a day. Days 2, 3, and 4: The doctor will increase each daily dose by 25 to 50 milligrams, taken either two or three times a day. Day 5 and up: If needed, the doctor may increase each dose by 25 to 50 milligrams every 2 or more days.
BIPOLAR MANIA (SHORT-TERM TREATMENT OF ACUTE EPISODES)
Adults
The usual dosage range is 400 to 800 milligrams a day. Doses above 800 milligrams a day have not been tested for safety. The dosage will be gradually increased over 4 to 6 days until the most effective dose is reached, using the following schedule: Day 1: Take 50 milligrams twice a day. Day 2: The doctor will increase the dose to 100 milligrams twice a day. Day 3: The doctor will increase the dose to 150 milligrams twice a day. Day 4: The doctor will increase the dose to 200 milligrams twice a day. Days 5 and 6: If needed, the doctor may increase each dose by no more than 200-milligram increments to a total daily dose of 800 milligrams.
BIPOLAR DEPRESSION
Adults
The usual dose is 300 milligrams once a day at bedtime. The dosage will be gradually increased over 4 days using the following schedule: Day 1: Take 50 milligrams at bedtime. Day 2: The doctor will increase the dose to 100 milligrams at bedtime. Day 3: The doctor will increase the dose to 200 milligrams at bedtime. Day 4: The doctor will increase the dose to 300 milligrams at bedtime.






