Seroquel

BIPOLAR MANIA (SHORT-TERM TREATMENT OF ACUTE EPISODES)

Adults

The usual dosage range is 400 to 800 milligrams a day. Doses above 800 milligrams a day have not been tested for safety. The dosage will be gradually increased over 4 to 6 days until the most effective dose is reached, using the following schedule: Day 1: Take 50 milligrams twice a day. Day 2: The doctor will increase the dose to 100 milligrams twice a day. Day 3: The doctor will increase the dose to 150 milligrams twice a day. Day 4: The doctor will increase the dose to 200 milligrams twice a day. Days 5 and 6: If needed, the doctor may increase each dose by no more than 200-milligram increments to a total daily dose of 800 milligrams.

DOSAGE ADJUSTMENT

If you have liver problems, you may be started at 25 milligrams a day. The doctor will increase the dose as needed in increments of 25 to 50 milligrams a day based on your body's response.

The dosage may also need to be lowered if you are weak, elderly, or prone to low blood pressure reactions. You may also need your dose adjusted if you're taking certain drugs, including Dilantin, Tegretol, and phenobarbital.

Overdosage

Any medication taken in excess can have serious consequences. If you suspect an overdose, seek medical help immediately.

• Symptoms of Seroquel overdose may include:
  Dizziness, drowsiness, fainting, rapid heartbeat