Silvadene Cream 1%

Pronounced: SIL-vuh-deen
Generic name: Silver sulfadiazine

Why is Silvadene Cream 1% prescribed?

Silvadene Cream 1% is applied directly to the skin. The cream is used along with other medications to prevent and treat wound infections in people with second- and third-degree burns. It is effective against a variety of bacteria as well as yeast.

Most important fact about Silvadene Cream 1%

Silvadene is a sulfa derivative. If burn wounds cover extensive areas of the body, Silvadene may be absorbed into the bloodstream, and if you have ever had an allergic reaction to sulfa drugs, such as Bactrim or Septra, this could lead to a similar reaction. Make sure your doctor is aware of any drug reactions you have experienced.

How should you use Silvadene Cream 1%?

Silvadene cream is for external use only.

Bathe the burned area daily.

You should continue using Silvadene Cream until the area has healed or is ready for skin grafting.

Clean your skin and apply Silvadene with a sterile, gloved hand. Apply a thin layer (about one-sixteenth of an inch) to the affected area.

--If you miss a dose...

Keep the burn areas covered with Silvadene at all times. Reapply the medicine if it is rubbed or washed off.

--Storage instructions...

Silvadene can be stored at room temperature.

What side effects may occur?

Side effects cannot be anticipated. If any side effects develop or change in intensity, tell your doctor immediately. Only your doctor can determine whether it is safe for you to continue using Silvadene.

• More common side effects may include:
  Areas of dead skin, burning sensation, red and raised rash on the body, skin discoloration

Why should Silvadene Cream 1% not be prescribed?

You should not use Silvadene if you are allergic to sulfa drugs such as Bactrim or Septra.

Do not use Silvadene at the end of pregnancy, on premature infants, or on newborn infants during the first 2 months of life.

Special warnings about Silvadene Cream 1%

Make sure your doctor knows about any kidney or liver problems you may have. If either organ becomes impaired, it may be necessary to stop using Silvadene.

There is a small chance of fungal infection when using Silvadene.