Sonata

Severe allergic reactions--including life-threatening ones that can cause severe breathing problems--have been reported and may require immediate medical care. Signs of a severe reaction include agitation, difficulty breathing, sudden drop in blood pressure, fainting, tingling sensations, itchy and flushed skin, hives, and swelling. If you are allergic to FD&C Yellow No. 5 (tartrazine), you'll probably want to avoid Sonata, which contains this substance.

The safety and effectiveness of Sonata have not been studied in children.

Possible food and drug interactions when taking Sonata

Avoid alcoholic beverages when taking Sonata; the drug increases alcohol's effect. Also forgo high-fat meals immediately before taking Sonata; they tend to slow or reduce the drug's effect.

If Sonata is used with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Sonata with the following:

Carbamazepine (Tegretol)
Cimetidine (Tagamet)
Diphenhydramine (Benadryl)
Imipramine (Tofranil)
Phenobarbital
Rifampin (Rifadin)
Thioridazine (Mellaril)

Special information if you are pregnant or breastfeeding

Sonata can affect a developing baby, especially during the last weeks before delivery, and is therefore not recommended for use during pregnancy. This drug also appears in breast milk and should not be used if you are nursing your baby.

Recommended dosage

ADULTS

The usual dose is 10 milligrams taken once daily at bedtime. Your doctor may adjust the dose to your individual need, especially if you are in a weakened condition or have a low body weight. A dose of 5 milligrams is recommended if you have liver disease or use the drug cimetidine.

OLDER ADULTS

The usual dose for older adults is 5 milligrams, as they may be more sensitive to the effects of Sonata.

Overdosage

An overdose of drugs such as Sonata can be fatal. If you suspect an overdose, seek medical attention immediately.

• Symptoms of Sonata overdose may include:
  Drowsiness, mental confusion, grogginess, lack of coordination, flaccid muscles, labored breathing, coma