Starlix

If you have liver disease, use Starlix with caution. Also, be aware that dialysis treatments may reduce the effectiveness of the drug.

The safety and effectiveness of Starlix in children have not been established.

Possible food and drug interactions when taking Starlix

If Starlix is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Starlix with the following:

Airway-opening drugs such as Alupent and Proventil
Aspirin
Beta blockers such as the blood pressure medications Inderal and Tenormin
Corticosteroids such as prednisone (Deltasone)
Decongestants such as Sudafed
MAO inhibitors such as the antidepressants Nardil and Parnate
Nonsteroidal anti-inflammatory drugs such as Advil, Motrin, and Naprosyn
Salicylates such as the arthritis drugs Disalcid and Trilisate
Thiazide diuretics such as the water pills Esidrix and HydroDIURIL
Thyroid medications such as Synthroid

Be careful about drinking alcohol, since excessive alcohol consumption can cause low blood sugar. Also be careful when having a liquid meal; it could reduce the effectiveness of the drug.

Special information if you are pregnant or breastfeeding

Because the effects of Starlix on the unborn child have not been adequately studied, this drug should not be used during pregnancy. Since studies suggest the importance of maintaining normal blood sugar levels during pregnancy, you may need to take insulin instead.

It is not known whether Starlix appears in breast milk. Because of potential harm to the baby, you'll need to choose between breastfeeding and continuing treatment with Starlix.

Recommended dosage

ADULTS

Take Starlix shortly before meals. The usual dose of Starlix, whether taken alone or combined with Actos, Avandia, or Glucophage, is 120 milligrams three times a day. If your doctor finds that your glycosylated hemoglobin (HbA1C) levels are near normal before you start taking the drug, you may use the lower dose of 60 milligrams three times a day.

Overdosage

An overdose of Starlix can cause low blood sugar. (For symptoms, see "What side effects may occur?") Mild hypoglycemia can usually be corrected by eating sugar or a sugar-based product. If your symptoms persist or worsen, seek medical attention immediately.