Topamax

If you are also taking Dilantin or Tegretol, the dosage of Topamax may need adjustment.

For Prevention of Migraine Headaches

The recommended total daily dose is 100 milligrams a day, taken in two divided doses. Your doctor will increase the dose slowly over 4 weeks. The usual regimen is as follows: Week 1: No morning dose; take 25 milligrams at night. Week 2: Take 25 milligrams in the morning and again at night. Week 3: Take 25 milligrams in the morning and 50 milligrams at night. Week 4: Take 50 milligrams in the morning and again at night.

CHILDREN

The usual daily dose for children 2 to 16 years of age is 5 to 9 milligrams for every 2.2 pounds of body weight, divided into two doses. Topamax therapy usually begins with a dose of 25 milligrams (or less) once daily during the first week. The daily dosage is then increased each week until the doctor is satisfied with the patient's response. It may take eight weeks to reach the ideal dose.

DOSAGE ADJUSTMENT

For people with poor kidney function, the dosage is usually cut in half. On the other hand, those undergoing hemodialysis may need a supplemental dose. Likewise, the doctor may adjust your dosage if you have liver problems.

Overdosage

Any medication taken in excess can have serious consequences. If you suspect an overdose of Topamax, seek medical attention immediately.

• Symptoms of Topamax overdose may include:
  Abdominal pain, agitation, blurred vision, convulsions, depression, dizziness, double vision, drowsiness, impaired coordination, impaired mental activity, low blood pressure, reduced consciousness, severe diarrhea, sluggishness, speech problems

A Topamax overdose may result in metabolic acidosis (see "Special warnings about this medication").