Trilisate

If you are sensitive to or have ever had an allergic reaction to Trilisate or drugs of this type, such as aspirin, you should not take this medication. Make sure your doctor is aware of any drug reactions you have experienced.

Special warnings about Trilisate

Use Trilisate with caution if you have severe or recurring kidney or liver disorder, gastritis (inflammation of the stomach lining), or a stomach or intestinal ulcer. Be cautious, too, if you routinely have three or more alcoholic drinks per day. This increases the risk of stomach problems.

If you are an asthmatic allergic to aspirin, tell your doctor before taking Trilisate.

It may be 2 to 3 weeks before you feel the effect of this medication.

If you are an older adult, you are more likely to suffer side effects from Trilisate.

Possible food and drug interactions when taking Trilisate

If Trilisate is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Trilisate with the following:

• Antacids such as Gaviscon and Maalox
• Antigout medications
• Blood-thinners such as Coumadin
• Carbonic anhydrase inhibitors such as acetazolamide (Diamox) used to treat heart failure, the eye condition called glaucoma, and certain convulsive disorders
• Diabetes medications such as insulin, Micronase, and Tolinase
• Methotrexate, an anticancer drug
• Other salicylates used to reduce fever, inflammation, and pain, such as aspirin
• Phenytoin (the seizure medication Dilantin)
• Steroids such as prednisone
• Valproic acid (the seizure medication Depakene)

Special information if you are pregnant or breastfeeding

The effects of Trilisate during pregnancy have not been adequately studied. If you are pregnant or plan to become pregnant, inform your doctor immediately. This drug does appear in breast milk and could affect a nursing infant. If this medication is essential to your health, your doctor may advise you not to breastfeed until your treatment is finished.