Trizivir

Pronounced: TRY-zuh-vir
Generic ingredients: Abacavir, Lamivudine, Zidovudine

Why is Trizivir prescribed?

Trizivir combines three drugs used to fight HIV, the deadly virus that undermines the immune system, leaving the body ever more vulnerable to infection, and eventually leading to AIDS. The components of Trizivir are all members of the category of HIV drugs known as nucleoside analogs:

Abacavir (also called Ziagen)
Lamivudine (also called Epivir or 3TC)
Zidovudine (also called Retrovir, AZT, or ZDV)

Trizivir may be prescribed alone or in combination with other HIV drugs. It reduces the amount of HIV in the bloodstream, but does not completely cure the disease. You may still develop the rare infections and other complications that accompany HIV. Remember, too, that Trizivir does not reduce the risk of transmitting the virus to others.

Most important fact about Trizivir

The abacavir (Ziagen) component of this medication which can cause a serious, possibly fatal allergic reaction. You should stop taking Trizivir and seek immediate medical attention if you develop any of the following symptoms: abdominal pain, body aches, cough, diarrhea, extreme fatigue, fever, general ill feeling, nausea, shortness of breath, skin rash, severe peeling skin, sore throat, vomiting. These symptoms usually appear during the first 6 weeks of therapy, but may occur any time during treatment. If they do occur, do not take another dose of Trizivir until you've seen your doctor.

If you have to stop taking Trizivir because of this allergic reaction, you must never take Trizivir or Ziagen again. Once you've had such a reaction, taking either drug could lead to death within hours.

When your prescription for Trizivir is filled, the pharmacist will give you a "warning card" that lists the symptoms of an allergic reaction. Be sure to read it and to carry it with you.

How should you take Trizivir?

Trizivir is usually taken twice a day, with or without food. It is important to take the medication exactly as prescribed and not to miss any doses. Be sure to refill your prescription before your supply runs out. If HIV drugs are stopped for even a short time, the virus can increase rapidly and may become harder to treat.

--If you miss a dose...