Uniretic

If you have liver disease or a disease of connective tissue called lupus erythematosus, Uniretic should be used with caution. Tell your doctor immediately if you notice a yellowish color to your skin or the whites of your eyes.

While taking Uniretic, do not use potassium supplements, salt substitutes that contain potassium, or diuretics that leave potassium levels high (such as Dyrenium and Moduretic) unless your doctor recommends it.

Diuretics such as the one in Uniretic sometimes leave the body with too little sodium, chloride, or potassium, leading to symptoms such as dry mouth, thirst, weakness, sluggishness, drowsiness, restlessness, muscle pain or cramps, muscular fatigue, low urine output, rapid heartbeat, nausea, and vomiting. If you develop any of these symptoms, alert your doctor.

Uniretic can aggravate diabetes or high cholesterol. If you have one of these conditions, your doctor should closely monitor your blood sugar or cholesterol levels.

If you develop unusual or increased coughing, tell your doctor. Contact your doctor immediately if you develop a sore throat or fever; they could be signs of a more serious illness.

If you are having a surgical procedure that requires anesthesia, make sure the doctor knows that you are taking Uniretic.

Possible food and drug interactions when taking Uniretic

If Uniretic is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Uniretic with the following:

• ACTH
• Alcohol
• Barbiturates such as phenobarbital or Seconal
• Cholestyramine (Questran)
• Colestipol (Colestid)
• Diabetes medications such as glyburide and insulin
• Guanabenz (Wytensin)
• Lithium (Lithobid, Lithonate)
• Narcotics such as Percocet
• Nonsteroidal anti-inflammatory painkillers such as Motrin and Naprosyn
• Potassium-sparing diuretics such as Dyrenium or Moduretic
• Potassium supplements such as Slow K
• Propantheline (Pro-Banthine)
• Salt substitutes containing potassium
• Steroid medications such as prednisone (Deltasone)