Wellbutrin

You should not take Wellbutrin if you currently have, or formerly had, an eating disorder. For some reason, people with a history of anorexia nervosa or bulimia seem to be more likely to experience Wellbutrin-related seizures. Do not take Wellbutrin if, within the past 14 days, you have taken a monoamine oxidase (MAO) inhibitor such as the antidepressants phenelzine or tranylcypromine. This particular drug combination could cause you to experience a sudden, dangerous rise in blood pressure.

Special warnings about Wellbutrin

In clinical studies, antidepressants increased the risk of suicidal thinking and behavior in children and adolescents with depression and other psychiatric disorders. Anyone considering the use of Wellbutrin or any other antidepressant in a child or adolescent must balance this risk with the clinical need. Wellbutrin has not been studied in children or adolescents and is not approved for treating anyone less than 18 years old.

Additionally, the progression of major depression is associated with a worsening of symptoms and/or the emergence of suicidal thinking or behavior in both adults and children, whether or not they are taking antidepressants. Individuals being treated with Wellbutrin and their caregivers should watch for any change in symptoms or any new symptoms that appear suddenly—especially agitation, anxiety, hostility, panic, restlessness, extreme hyperactivity, and suicidal thinking or behavior—and report them to the doctor immediately. Be especially observant at the beginning of treatment or whenever there is a change in dose.

Be sure to let the doctor know if you have heart trouble, liver problems, or kidney disease before you start taking Wellbutrin. Use this drug with extreme caution if you have cirrhosis of the liver.

Stop taking Wellbutrin and call your doctor immediately if you have difficulty breathing or swallowing; notice swelling in your face, lips, tongue, or throat; develop swollen arms and legs; or break out with itchy eruptions. These are warning signs of a potential severe allergic reaction.