Zerit

Why should Zerit not be prescribed?

If Zerit gives you an allergic reaction, you should not take the drug.

Special warnings about Zerit

Remember that Zerit does not prevent the spread of HIV through sexual contact or contact with infected blood.

Zerit has been known to cause severe and even fatal liver damage, especially in women, overweight individuals, and people who have been taking Zerit or similar medications for a long time. The risk increases if you're being treated with a combination of Zerit, Videx, and hydroxyurea. Signs of a liver problem include weakness, fatigue, abdominal pain, nausea, vomiting, and shortness of breath. If you develop these symptoms, call your doctor immediately; treatment with Zerit may have to be stopped. Also be sure to tell the doctor if you've ever had a liver problem or tend to abuse alcohol; the doctor will watch especially closely for any sign of a liver problem.

Zerit can also cause serious and even fatal pancreatitis, especially if you've had the problem in the past, suffer from gallstones, or drink alcoholic beverages. Combining Zerit with Videx increases the risk. Check with your doctor immediately if you develop such signs of pancreatitis as stomach pain, nausea, or vomiting; you may have to stop treatment with Zerit. If you have any of the risk factors for pancreatitis, make sure the doctor is aware of it.

One of the more common and dangerous side effects of Zerit is a problem called peripheral neuropathy, a serious condition in which certain nerves are damaged. If you notice numbness, tingling, or pain in your hands or feet, notify your physician immediately. Treatment with Zerit may have to be stopped.

Another side effect seen in some people receiving drugs for HIV is a redistribution of body fat, leading to extra fat around the middle, a "buffalo hump" on the back, and wasting in the arms, legs, and face. Researchers don't know whether this represents a long-term health problem or not.

The benefit you get from Zerit may not last long. If your symptoms begin to get worse, tell your doctor immediately.