Zestoretic

Special information if you are pregnant or breastfeeding

During the second and third trimesters, lisinopril can cause birth defects, prematurity, and death in the fetus and newborn. If you are pregnant or plan to become pregnant, contact your doctor immediately to discuss the potential hazard to your unborn child. Zestoretic may appear in breast milk and could affect a nursing infant. If this medication is essential to your health, your doctor may advise you to discontinue breastfeeding until your treatment with this medication is finished.

Recommended dosage

ADULTS

Zestoretic is designed to replace higher doses of either component. Dosages of the lisinopril component range from 10 to 80 milligrams a day; dosages of hydrochlorothiazide typically fall between 6.25 and 50 milligrams daily. If either component, when prescribed alone, fails to control your blood pressure, your doctor may try the Zestoretic combination, starting with either 10 or 20 milligrams of lisinopril and 12.5 milligrams of hydrochlorothiazide, and gradually increasing the dosage as needed.

If you are age 65 or older, or have kidney problems, your doctor will adjust your dosage with caution. This drug is not prescribed for people with severe kidney damage.

CHILDREN

Safety and effectiveness in children have not been established.

Overdosage

Any medication taken in excess can have serious consequences. If you suspect an overdose, seek medical treatment immediately.

• Symptoms of Zestoretic overdose may include:
  Dehydration, low blood pressure