Ziac

Pronounced: ZIGH-ack
Generic ingredients: Bisoprolol fumarate, Hydrochlorothiazide

Why is Ziac prescribed?

Ziac is used to treat high blood pressure. It combines a beta-blocker (bisoprolol, which is the ingredient in the drug Zebeta) with a thiazide diuretic (hydrochlorothiazide). Beta-blockers decrease the force and rate of heart contractions, thus lowering blood pressure. Diuretics help your body produce and eliminate more urine, which also helps lower blood pressure.

Most important fact about Ziac

Ziac does not cure high blood pressure; it merely keeps it under control. Therefore, you must continue taking it even if you are feeling well. Do not stop taking Ziac unless instructed to do so by your doctor. This is especially important if you have coronary artery disease. Abruptly stopping Ziac could cause chest pain, heart rhythm problems, and even heart attack.

How should you take Ziac?

Take Ziac exactly as prescribed, even if your symptoms have disappeared. Try not to miss any doses. If this medication is not taken regularly, your condition may worsen.

--If you miss a dose...

Take the missed dose as soon as possible. However, if it is almost time for your next dose, skip the one you missed and go back to your regular schedule. Never take 2 doses at once.

--Storage instructions...

Store at room temperature in a tightly closed container.

What side effects may occur?

Side effects cannot be anticipated. If any develop or change in intensity, inform your doctor as soon as possible. Only your doctor can determine whether it is safe for you to continue taking Ziac.

• More common side effects may include:
  Dizziness, fatigue

Additional side effects have been reported with Ziac, although it's unknown if the drug was the cause. Be sure to tell your doctor about any unusual or severe symptoms.

Why should Ziac not be prescribed?

Do not take Ziac if you have inadequate blood supply to the circulatory system (cardiogenic shock), certain types of irregular heartbeat, a slow heartbeat, bronchial asthma, or severe congestive heart failure. Also avoid the drug if you have trouble urinating.

Do not use Ziac if you have an allergic reaction to the drug or if you're allergic to antibiotics known as sulfonamides (such as Bactrim, Cotrim, and Septra).