Zoladex

Pronounced: ZO-luh-dex
Generic name: Goserelin acetate

Why is Zoladex prescribed?

Zoladex relieves the symptoms of advanced prostate cancer in men and advanced breast cancer in premenopausal women. In combination with other forms of therapy, it is also prescribed during treatment of early prostate cancer.

In addition, it can be used in the treatment of endometriosis, a condition in which tissue from the lining of the uterus invades the abdomen. If you are scheduled for surgical removal of the lining, the drug may be used to thin the lining prior to the operation.

Zoladex works by reducing levels of testosterone in men and estrogen in women. These hormones can encourage the growth of certain cancers.

Most important fact about Zoladex

Symptoms may actually get worse during the first few weeks of therapy. However, as hormone levels subside, you should begin to feel an improvement.

How should you take Zoladex?

Doses are implanted under the skin of the upper abdomen every 4 or 12 weeks by your physician or a nurse.

--If you miss a dose...

Make an appointment as soon as possible.

What side effects may occur?

Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue using Zoladex.

• More common side effects may include:
  Acne, application site reactions, breast development in men or enlargement in women, breast tenderness or pain, change in sex-drive, depression, dizziness, emotional problems, flu symptoms, fluid retention and swelling, hair growth in women, headache, hot flashes, infection, insomnia, lethargy, loss of appetite, loss of breast tissue in women, lung problems, nausea, nervousness, pain, rash, sexual impairment, sore throat, sweating, urinary problems, vaginal dryness, vaginal inflammation, voice changes, weak heart, weakness, weight gain

Why should Zoladex not be prescribed?

If Zoladex gives you an allergic reaction, it cannot be used. It should also be avoided during pregnancy and breastfeeding, and if you have unexplained abnormal vaginal bleeding. Women of childbearing age should use nonhormonal contraceptive measures while taking Zoladex.