Zyflo

Because Zyflo can affect the liver, make sure your doctor is aware of any problems you've had in the past. Warn the doctor, too, if you're a heavy drinker. Your liver function will be tested before you start Zyflo, and regularly thereafter. Be sure to go in for these tests. If they reveal liver damage, you'll have to stop taking Zyflo. Also be sure to tell your doctor immediately if you develop any symptoms of liver disease. These include pain in the upper right abdomen, nausea, fatigue, lethargy, itching, general discomfort, and jaundice (yellowing of the skin and eyes).

Possible food and drug interactions when taking Zyflo

If Zyflo is taken with certain other drugs, the effects of either could be increased, decreased, or altered. You should check with your doctor before stopping or starting any prescription or nonprescription medicine. This is especially important with the following:

• Astemizole
• Beta blockers (a type of heart and blood pressure medication)
• Calcium channel blockers (another type of heart and blood pressure medication)
• Cisapride
• Cyclosporin
• Terfenadine
• Theophylline
• Warfarin

While you are taking Zyflo, your theophylline dosage may need to be lowered, and your theophylline levels will have to be carefully watched. Dosages of propanolol may also need reduction, and warfarin dosages may need adjustment as well.

Special information if you are pregnant or breastfeeding

The effects of Zyflo in pregnancy have not been adequately studied. If you are pregnant or plan to become pregnant, ask your doctor whether you should continue taking Zyflo. It is not certain that the drug appears in breast milk, but taking Zyflo while nursing is not recommended. Discuss with your doctor whether it's best to stop taking the drug or to give up breastfeeding.

Recommended dosage for Zyflo

ADULTS

The recommended dosage is one 600-milligram tablet 4 times a day.

CHILDREN

The safety and effectiveness of this drug in children under 12 years of age have not been established.

Overdosage

Because Zyflo is a relatively new drug, little is known about overdosage. However, any medication taken in excess can have serious consequences. If you suspect an overdose, seek medical treatment immediately.