Zyloprim

Because Zyloprim may make you drowsy, do not drive or perform hazardous tasks until you know how the medication affects you.

It may be 2 to 6 weeks before you see any results from this medication.

Possible food and drug interactions when taking Zyloprim

If Zyloprim is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Zyloprim with the following:

Amoxicillin (Amoxil, Trimox, Wymox)
Ampicillin (Omnipen, Principen)
Azathioprine (Imuran)
Blood thinners such as Coumadin
Cyclosporine (Sandimmune, Neoral)
Drugs for diabetes, such as Diabinese and Orinase
Mercaptopurine (Purinethol)
Probenecid (Benemid, ColBENEMID)
Sulfinpyrazone (Anturane)
Theophylline (Theo-Dur, Slo-Phyllin, and others)
Thiazide diuretics such as HydroDIURIL, Diuril, and others
Vitamin C

Special information if you are pregnant or breastfeeding

The effects of Zyloprim during pregnancy have not been adequately studied. If you are pregnant or plan to become pregnant, notify your doctor immediately. Zyloprim should be taken during pregnancy only if it is clearly needed.

Zyloprim appears in breast milk; what effect it may have on a nursing baby is unknown. Caution is advised when Zyloprim is taken during breastfeeding.

Recommended dosage

ADULTS

Your doctor will tailor the dosage of Zyloprim individually to control the severity of symptoms and to bring the uric acid levels to normal or near normal.

Gout

The usual starting dose is 100 milligrams once daily. Your doctor may increase your dose by 100 milligrams per day at 1-week intervals until desired results are attained. The average dose is 200 to 300 milligrams per day for mild gout and 400 to 600 milligrams daily for moderate to severe gout. The most you should take in a day is 800 milligrams.

Recurrent Kidney Stones

The usual dose is 200 to 300 milligrams daily, divided into smaller doses or taken as one dose.

Management of Uric Acid Levels in Certain Cancers