Xifaxan

Pronounced: zuh-FAX-in
Generic name: Rifaximin

Why is Xifaxan prescribed?

Xifaxan is an antibiotic prescribed to treat traveler's diarrhea, a bacterial infection in the intestines caused by Escherichia coli (also called E. coli). Traveler's diarrhea is the result of eating contaminated food or drinking untreated water, usually in foreign countries. Xifaxan is not prescribed for diarrhea that occurs with a fever or bloody stools, or when the diarrhea is not due to E. coli.

Most important fact about Xifaxan

Like all antibiotics, Xifaxan could cause a severe inflammation of the colon (known as pseudomembranous colitis). It results from bacterial overgrowth in the colon and ranges in severity from mild to life-threatening. Contact your doctor right away if you develop any of the following:

• Abdominal cramps
• Watery diarrhea
• Frequent bowel movements
• Low-grade fever
• Bloody stools

How should you take Xifaxan?

Xifaxan can be taken with food or on an empty stomach. It is best to take it at evenly spaced intervals throughout the day to keep a constant supply in the bloodstream.

--If you miss a dose...

Take the forgotten dose as soon as you remember. However, if it is almost time for your next dose, skip the one you missed and return to your regular schedule. Do not take two doses at once.

--Storage instructions...

Store at room temperature.

What side effects may occur?

Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe to continue using Xifaxan.

• More common side effects may include:
  Abdominal pain, constipation, fever or high body temperature, gas, headache, nausea, painful or urgent bowel movements, vomiting

Why should Xifaxan not be prescribed?

Do not take Xifaxan if you are allergic to it or if you have ever had an allergic reaction to other rifamycin antibiotics, such as rifabutin (Mycobutin), rifampin (Rifadin, Rimactane), and rifapentine (Priftin).